S63845 resistance mechnism
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP290994
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资源简介：
MCL-1 plays a central role in B-cell lymphoma progression and drug resistance. Pharmacologically targeting MCL-1, therefore, represents an attractive strategy to combat these lymphomas. S63845, a MCL1 inhibitor, was shown to have high response rates in mantle cell lymphoma (MCL) and burkitt lymphoma. Overall design: RNA sequencing to profile expression in paired parental and S63845 resistant lymphoma cell lines
创建时间：
2022-12-02
