Spike variant predictions
收藏资源简介：
Spike variant glycosylation predictions. (spike_mut_idx.v3.xlsx) > Glycoimpact*: likelihood the glycosylation of a proximal site is perturbed > mannoseDist*: aggregate Fisher log-OR for any high-mannose (>5mannose) structure (taken from IMRs). LIkelihood high-mannose structures, in general, will increase or decrease > IMR - Expected Change: a combination of proximity information with mannoseDist to estimate joint effect > IMR/InSaNNE prediction: predictions of differential glycosylation from IMRs or InSaNNE respectively *_seq refers to sequence-based predictions, _str refers to structure-based predictions Generating R code is also provided without raw-data
刺突蛋白变体糖基化预测（数据集文件：spike_mut_idx.v3.xlsx） > Glycoimpact*：糖基化影响度（Glycoimpact），即近端糖基化位点发生扰动的可能性 > mannoseDist*：甘露糖分布度（mannoseDist），指取自IMRs的、所有甘露糖残基数量＞5的高甘露糖结构的汇总Fisher对数优势比，用于反映总体上高甘露糖结构丰度的增减趋势 > IMR-预期变化量：结合邻近位点信息与mannoseDist以评估联合效应 > IMR/InSaNNE预测：分别基于IMRs与InSaNNE模型得到的差异糖基化预测结果 > 后缀_seq代表基于序列的预测，_str代表基于结构的预测 > 本数据集附带生成所需的R代码，但未提供原始数据
