Ubiquitylation of H2B on lysine 120 (H2Bub) is associated with active transcriptional elongation. H2Bub has been implicated in histone cross-talk and is generally regarded to be a prerequisite for H3K

NIAID Data Ecosystem50

Both H4K20 mono-methylation and H3K56 acetylation mark transcription-dependent histone turnover in fission yeast. Schizosaccharomyces pombe

组蛋白修饰

转录调控

Nucleosome dynamics facilitated by histone turnover is required for transcription as well as DNA replication and repair. Histone turnover is often associated with various histone modifications such as

NIAID Data Ecosystem40

Profiling of H3K9cr and H3K9ac in the P19 embryonal carcinoma cells

组蛋白修饰

细胞分化表观遗传学

To gain a deeper insight into dynamic changes of H3K9cr and H3K9ac during cell fate commitment, ChIP-seq was performed to analyze the genome-wide changes of H3K9cr and H3K9ac during neuroectodermal di

NIAID Data Ecosystem60

Role of CxxC-finger Protein 1 in the Establishment of Epigenetic Landscapes in Mouse Oocytes. Role of CxxC-finger Protein 1 in the Establishment of Epigenetic Landscapes in Mouse Oocytes

细胞表观遗传学

组蛋白修饰

During oogenesis, oocytes gain competence to accomplish meiotic maturation and prepare for embryonic development following fertilization. Trimethylated histone H3 on lysine-4 (H3K4me3) mediates a wide

NIAID Data Ecosystem40

Nitric oxide regulates gene expression in cancers by controlling histone posttranslational modifications

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