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Preparation of Trifluorostyrenes via Palladium-Catalyzed Coupling of Arylboronic Acids with Chloro- and Bromotrifluoroethylene

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Preparation_of_Trifluorostyrenes_via_Palladium_Catalyzed_Coupling_of_Arylboronic_Acids_with_Chloro_and_Bromotrifluoroethylene/2468233
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A highly efficient and cost-effective method for the preparation of α,β,β-trifluorostyrene (TFS) and its derivatives is described. The method required only 0.2 mol % of Pd­(dba)2 and 0.4 mol % of PtBu3 and occurred to full conversion within 2.0 h. With this method, a wide range of arylboronic acids were efficiently incorporated to generate α,β,β-trifluorostyrene derivatives.
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2016-02-20
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