five

Proteomics analysis of lipid-induced granules

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NIAID Data Ecosystem2026-05-10 收录
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https://www.omicsdi.org/dataset/pride/PXD064747
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During the processes of MAFLD and MASH, DDX49 undergoes liquid-liquid phase separation. Subsequently, we used OA/PA (2:1) to simulate the MASH model in vitro. After treating HHL5 cells with OA/PA for 24 hours, we separated the lipid-organized particles of DDX49 by differential centrifugation. To investigate the composition of these particles and study their functions, we conducted a 10-fold proteomic analysis.
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2026-01-09
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