Average sequencing depth of the genome sequences of the phages included in the community at different passages and lines.

A correction was applied for pairs of closely related phages at depth ratios below 20/80 (Phages B and C). Mutations detected at passage 0 in the read mapping of each phage at a consistent specific ratio corresponded to discrepancies between the phages. We calculate the relative proportion of mapped reads corresponding to each phage by calculating the average of the frequency at which each mutation appears. We multiply this value (from 0 to 1) by the total number of reads mapped. We cannot apply this correction for pairs of close relative phages where the ratio is close to 50−50 (Phages I and J, and G and H. These phages are represented together).
(XLSX)