Study on the functional mechanism of NOP2 in regulating lung cancer development

NOP2 is a member of the NOL1/NOP2/SUN structural domain (NSUN) family and is responsible for catalyzing post-transcriptional modification of RNA via 5-methylcytosine (m5C). m5C modification dysregulation has been implicated in the pathogenesis of a variety of malignancies. Here, we investigated the expression of NOP2 in lung cancer tissues and cells and found that its expression was significantly upregulated. This is consistent with previous reports. To further investigate the mechanism by which NOP2 affects lung cancer development, RNA sequence analysis was performed. In conclusion, our study emphasizes the important role of NOP2 in lung cancer, and its promise as a potential target for lung cancer therapy. To investigate the mechanism by which NOP2 affects lung cancer development, RNA sequence analysis was performed.