RNA sequencing analysis of the hippocampus reveals transcriptomic signatures of PTZ-kindled seizure rats and upon treatment of novel anti-convulsant chemical Q808

The present study aimed to use RNA sequencing (RNA-seq) to reveal the gene transcriptomic profile of chronic PTZ-kindled seizure rats and the difference of the PTZ model rat before and after treatment with Q808. Overall design: Rats were randomly divided into vehicle control group (n=3), PTZ + vehicle group (n=3), and PTZ + Q808 group (n=2)