Macrocyclic inhibitors targeting the prime site of the fibrinolytic serine protease plasmin

Macrocyclic inhibitors targeting the prime site of the fibrinolytic serine protease plasmin Descriptor: (1r,4S)-4-(aminomethyl)-N-[(24S)-5-methyl-8,11,16,23-tetraoxo-7,10,15,22-tetraazatetracyclo[24.2.2.2~18,21~.1~2,6~]tritriaconta-1(28),2(33),3,5,18,20,26,29,31-nonaen-24-yl]cyclohexane-1-carboxamide, Plasminogen Authors: Guojie, W. Deposit date: 2024-03-11 Release date: 2024-10-30 Last modified: 2025-05-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin. Chemmedchem, 19, 2024靶向纤溶丝氨酸蛋白酶纤溶酶（plasmin）活性位点的大环抑制剂 描述符：(1r,4S)-4-(氨基甲基)-N-[(24S)-5-甲基-8,11,16,23-四氧代-7,10,15,22-四氮杂四环[24.2.2.2~18,21~.1~2,6~]三十三碳-1(28),2(33),3,5,18,20,26,29,31-壬烯-24-基]环己烷-1-甲酰胺、纤溶酶原（plasminogen） 作者：W. 国杰 提交日期：2024-03-11 发布日期：2024-10-30 最后修改日期：2025-05-21 检测方法：X射线衍射（2.1 埃） 引用文献：《靶向纤溶丝氨酸蛋白酶纤溶酶活性位点的大环抑制剂》，《Chemmedchem》，第19卷，2024年