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Sequencing of liver specimens from FXR knockout mice

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NIAID Data Ecosystem2026-05-01 收录
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To explore the downstream molecular mechanisms of lipid toxicity caused by FXR gene activation, we constructed a model of non-alcoholic fatty liver disease using wild-type mice and FXR knockout mice of the C56BL/6N strain on a 60% kcal high-fat diet for 14 weeks. At the end of the experiment, fresh liver samples were taken for mRNA sequencing.

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2024-03-10
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