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Isoquinolinone-induced inhibition of cAMP production in MT<sub>1</sub>-CHO and MT<sub>2</sub>-CHO cells.

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The pIC50 and %Inhmax were mean ± SEM of 2 trials done in duplicates. The corresponding IC50 values were calculated using the mean pIC50 values. a%Inhmax – Maximal percentage inhibition of the forskolin-elevated cAMP level. bNSR – no significant response for up to 10 µM of tested compounds in the assay buffer. cExtrapolated %Inhmax from non-linear regression. Isoquinolinone-induced inhibition of cAMP production in MT1-CHO and MT2-CHO cells.

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2014-12-05
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