GPCRs, class C metabotropic glutamate, pheromone

This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

本路径之构建，乃采用GPCRDB（Horn等，1998年），可通过http://www.gpcr.org/7tm/（最初位于http://www.cmbi.kun.nl/7tm/）访问。此类别分组乃基于GPCRDB中提供的GPCR系统发育树以及Karchin等人（生物信息学，2002年，第147-159页）所使用的训练集。标签则用以指示由上述参考文献所描述的GPCR各类别及其子代与孙代。