Dataset for: Deepwater Horizon crude oil exposure alters cholesterol biosynthesis with implications for developmental cardiotoxicity in larval mahi-mahi (Coryphaena hippurus)

Past studies have predicted cholesterol biosynthetic pathways in Mahi larvae are likely impacted by crude oil exposure. The goal of this project is to determine if the quantified gene expression changes in this pathway result in cholesterol changes in the larvae. Mahi larvae were exposed to varying sublethal concentrations of slick and source oil. Cholesterol in larvae was quantified using enzyme-linked absorbance assays and immunohistochemistry was used to visualize changes in cholesterol concentration and distribution. In addition, water quality was also obtained. This dataset supports the publication: McGruer, V., Pasparakis, C., Grosell, M., Stieglitz, J. D., Benetti, D. D., Greer, J. B., & Schlenk, D. (2019). Deepwater Horizon crude oil exposure alters cholesterol biosynthesis with implications for developmental cardiotoxicity in larval mahi-mahi (Coryphaena hippurus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 220, 31–35. doi:10.1016/j.cbpc.2019.03.001