Codes availability of article

All custom scripts used for single-cell and spatial transcriptomic data processing, integration, and visualization have been deposited in the Figshare. The repository contains R codes for raw data preprocessing, Seurat/Scanpy-based clustering, spatial mapping, cell–cell interaction analysis, trajectory inference, and figure generation. Detailed instructions for environment setup and execution are provided in the README file to enable full reproducibility of the analyses reported in this study.