Supplementary tables S1-S4. Comparison of two different host plant genera responding to grapevine leafroll-associated virus 3 infection

Grapevine leafroll-associated virus 3 (GLRaV-3) is one of the most important viruses of grapevine but, despite this, there remain several gaps in our understanding of its biology. Because of its narrow host range -limited to <em>Vitis</em> species - and because the virus is restricted to the phloem, most GLRaV-3 research has concentrated on epidemiology and the development of detection assays. The recent discovery that GLRaV-3 can infect <em>Nicotiana</em> <em>benthamiana, </em>a plant model organism, makes new opportunities available for research in this field. We used RNA-seq to compare both <em>V. vinifera </em>and <em>N. benthamiana</em> host responses to GLRaV-3 infection. This is the first analysis of gene expression profiles beyond <em>Vitis </em>to mealybug-transmitted GLRaV-3.葡萄卷叶相关病毒3（Grapevine leafroll-associated virus 3, GLRaV-3）是危害葡萄的主要病毒之一，但即便如此，学界对其生物学特性的认知仍存在诸多空白。由于其宿主范围狭窄——仅局限于<em>Vitis</em>物种——且病毒仅定位于韧皮部，因此绝大多数GLRaV-3相关研究都集中于流行病学调查与检测方法开发。近期有研究发现GLRaV-3可侵染植物模式生物本氏烟（<em>Nicotiana benthamiana</em>），这为该领域的研究带来了全新机遇。本研究采用RNA-seq技术，对比了<em>V. vinifera</em>与<em>N. benthamiana</em>两种宿主在GLRaV-3侵染后的应答反应。这是首次在葡萄属之外，针对粉蚧传播的GLRaV-3开展基因表达谱分析。