The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor

The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor Descriptor: HUMAN LEUKOCYTE ELASTASE, MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE, alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Bode, W, Wei, A-Z. Deposit date: 1991-10-24 Release date: 1994-01-31 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor. FEBS Lett., 234, 1988

人类白细胞弹性蛋白酶（human leukocyte elastase）与缬氨酸氯甲基酮抑制剂（valine chloromethyl ketone inhibitor）形成复合物的2.3埃分辨率精制晶体结构。描述项：人类白细胞弹性蛋白酶，甲氧基琥珀酰-丙氨酰-丙氨酰-脯氨酰-缬氨酸氯甲基酮（MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE），α-D-吡喃葡萄糖（alpha-D-glucopyranose）-(1→4)-2-乙酰氨基-2-脱氧-α-D-吡喃葡萄糖（alpha-D-glucopyranose）-(1→2)-β-D-吡喃甘露糖（beta-D-mannopyranose）-(1→6)-[α-D-吡喃甘露糖（alpha-D-mannopyranose）-(1→3)]β-D-吡喃甘露糖（beta-D-mannopyranose）-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（beta-D-glucopyranose）-(1→4)-[α-L-吡喃岩藻糖（alpha-L-fucopyranose）-(1→6)]2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（beta-D-glucopyranose）……作者：博德（Bode, W）、韦（Wei, A-Z）。入库日期：1991年10月24日；发布日期：1994年1月31日；最后修改日期：2024年7月10日。检测方法：X射线衍射（2.3 Å）。引用文献：人类白细胞弹性蛋白酶与缬氨酸氯甲基酮抑制剂复合物的2.3埃分辨率精制晶体结构。FEBS通讯（FEBS Lett.），第234卷，1988年。