Source data for the kinetic assays in publication "Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5′-monophosphate dehydrogenase"

Datasets of enzyme kinetics related to the publication "Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5′-monophosphate dehydrogenase". The underlying reference to the paper will be provided upon publication. Individual files contain raw kinetic reaction data of the mycobacterial IMPDHs (wild type and mutant forms of Mycobacterium smegmatis or wild type Mycobacterium tuberculosis). Individual data sets are presented as time data points of the absorbance at 340 nm in an Excel file with a linked Graphpad graphical link. Detailed experimental conditions are available in the related publication.本数据集关联于论文《底物协同性调控分枝杆菌肌苷5'-单磷酸脱氢酶的竞争性抑制剂响应》（Substrate cooperativity shapes competitive inhibitor responses in mycobacterial inosine 5′-monophosphate dehydrogenase），该论文的完整参考文献信息将在论文正式发表时提供。 各独立文件存储了分枝杆菌来源的肌苷5'-单磷酸脱氢酶（inosine 5′-monophosphate dehydrogenase, 简称IMPDH）的原始酶促反应动力学数据，涵盖耻垢分枝杆菌（Mycobacterium smegmatis）的野生型与突变型菌株，以及结核分枝杆菌（Mycobacterium tuberculosis）的野生型菌株。 各数据集以Excel文件格式存储，包含340 nm波长下的吸光度时间序列数据，并附带Graphpad绘图链接。详细实验条件请参阅本研究相关论文。