Central Genes in the Ingenuity Pathway Networks of differentially expressed transcripts/proteins in spleen leukocytes of 2 and 4 week old NOD mice.

aGenes that came from the list of differentially expressed genes in NOD mice compared to control strains (NON and C57BL/6). The connections to each gene (i.e. edges representing gene-gene relationships) in the molecular networks were manually counted. The central genes were then ranked from highest to lowest based on the number of total connections; cut-off, 4 total connections. Genes indicated in Bold text are central or focus genes that were common to both ages.