Comparison of metabolic ratios in parental, induced low-producing and induced high-producing cell lines.

The numbers in the left column correspond to the following metabolic ratios: 1: lactate production- to-glucose consumption, 2: Pyruvate branch point ratio, 3: percentage of pyruvate derived from glucose, 4: contribution of glucose to TCA cycle, 5: contribution of glutamine to TCA cycle, 6: contribution of other amino acids to TCA cycle, 7: specific ATP production rate (mmol (106 cells)-1h-1)), 8: percentage of ATP consumption for biomass synthesis, 9: percentage of ATP consumption for mAb synthesis.