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Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes. Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

NIAID Data Ecosystem2026-03-13 收录

胰岛细胞分化

单细胞多组学调控组

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA836317 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2022-05-08

细胞重编程

胰岛细胞分化

Direct lineage conversion of adult cells is a promising approach for regenerative medicine. A major challenge of lineage conversion is to generate specific subtypes of cells, closely related cells wi

NIAID Data Ecosystem40

Chromatin dynamics reveal circadian control of human in vitro islet maturation [WGBS]

胰岛细胞分化

表观遗传昼夜节律调控

Stem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic isle

NIAID Data Ecosystem30

Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human pancreatic islet cell specification. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human pancreatic islet cell specification

胰岛细胞分化

视黄酸信号通路

Retinoic acid (RA) signaling is essential for multiple developmental processes, including appropriate pancreas formation from the foregut endoderm. RA is also required to generate pancreatic progenito

NIAID Data Ecosystem20

Chromatin dynamics reveal circadian control of human in vitro islet maturation. Chromatin dynamics reveal circadian control of human in vitro islet maturation

精子染色质表观遗传学

胰岛细胞分化

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem30

microRNA and mRNA expression profiles of human pancreatic islet-like cell clusters. Homo sapiens

胰岛细胞分化

基因表达调控

Type 1 diabetes is an autoimmune destruction of pancreatic islet beta cell disease, and it is important to find new alternative source of the islet beta cells to replace the damaged cells. Human embry

NIAID Data Ecosystem30

Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes. Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

资源简介：

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