Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p]

Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p] Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of Interferon Genes Authors: Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E. Deposit date: 2015-07-08 Release date: 2015-08-26 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. Mol.Cell, 59, 2015

与3',3'-环二(3',5')腺苷酸（3',3' c-di-AMP，c[A(3',5')pA(3',5')p]）结合的星状海葵（Nematostella vectensis）干扰素基因刺激因子（Stimulator of Interferon Genes, STING）的晶体结构
描述符：(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-双(6-氨基-9H-嘌呤-9-基)八氢-2H,7H-二呋喃并[3,2-d:3',2'-j][1,3,7,9,2,8]四氧二磷杂环十二烷-3,5,10,12-四醇 5,12-二氧化物
干扰素基因刺激因子（Stimulator of Interferon Genes）
作者：Kranzusch, P.J.、Wilson, S.C.、Lee, A.S.Y.、Berger, J.M.、Doudna, J.A.、Vance, R.E.
存档日期：2015-07-08
发布日期：2015-08-26
最后修改日期：2024-03-06
实验方法：X射线衍射（分辨率2.95埃）
引用文献：《cGAS-STING通路的古老起源揭示通用2',3'-cGAMP信号传导机制》，《分子细胞》，59卷，2015年