Human proteins bound to RNA/DNA hybrid
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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP155244
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资源简介:
RNA/DNA hybrids form when RNA hybridizes with its template DNA generating a three-stranded structure known as the R-loop. Knowledge of how they form and resolve, and their functional roles are limited. Here, we identified proteins that bind to RNA/DNA hybrids. Overall design: We identified transcripts bound by SRSF1 using two independent methods PAR-CLIP and RNA-IP. Then we characterized R-loop regions in human cells using DRIP-seq with the S9.6 antibody.
创建时间:
2019-09-21



