Structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP linked isofagomine analog 3-5

Structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP linked isofagomine analog 3-5 Descriptor: 1-(5-O-{3-[(3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)piperidin-1-yl]propyl}-alpha-L-lyxofuranosyl)pyrimidine-2,4(1H,3H)-dione, GLYCEROL, MANGANESE (II) ION, ... Authors: Paparella, A.S, Gilaj, N, Wagner, A.G, Schramm, V.L, Ghosh, A. Deposit date: 2026-01-29 Release date: 2026-07-08 Last modified: 2026-08-05 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Isofagomine Derivatives as TcdB Glucosyltransferase Inhibitors. J.Med.Chem., 69, 2026