Risk of serious non-AIDS events associated with a low CD4/CD8 ratio (categorized by quartiles and by the cut-off of 0.4).

Seven subjects from the 407 individuals were not included in the multivariate analysis due to missing data on CD4 nadir/cumulative ART exposure.*Multivariate analysis adjusted by age, gender, nadir CD4+ cell count, date of ART initiation and cumulative ART exposure.†Case-control substudy matched by age, gender, nadir CD4+ cell count and proximal CD4+ cell count.§Conditional logistic regression analysis adjusted for date of ART initiation and cumulative ART exposure.