Ligand binding domain of the glucocorticoid receptor complexed with fluticazone furoate
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Ligand binding domain of the glucocorticoid receptor complexed with fluticazone furoate Descriptor: (6alpha,11alpha,14beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoan drosta-1,4-dien-17-yl furan-2-carboxylate, Glucocorticoid receptor, Tif2 coactivator motif Authors: Shewchuk, L.M, McLay, I, Stewart, E, Biggadike, K.B, Hassell, A.M, Bledsoe, R.K. Deposit date: 2008-03-18 Release date: 2008-06-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.84 Å) Cite: X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain. J.Med.Chem., 51, 2008
与糠酸氟替卡松（fluticazone furoate）结合的糖皮质激素受体（glucocorticoid receptor）配体结合结构域（ligand binding domain）
描述物：(6α,11α,14β,16α,17α)-6,9-二氟-17-[(氟甲基硫基)羰基]-11-羟基-16-甲基-3-氧代雄甾-1,4-二烯-17-基 呋喃-2-羧酸酯、糖皮质激素受体、Tif2共激活因子基序
作者：Shewchuk, L.M.、McLay, I.、Stewart, E.、Biggadike, K.B.、Hassell, A.M.、Bledsoe, R.K.
存入日期：2008-03-18
发布日期：2008-06-24
最后修改日期：2023-08-30
检测方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.84埃（Å）
引用：《新型高亲和力糖皮质激素激动剂糠酸氟替卡松的糖皮质激素受体-配体结合结构域X射线晶体结构》，《J. Med. Chem.》，第51卷，2008年
创建时间：
2008-03-18
