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The role of Itgb1 in islet development

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NIAID Data Ecosystem2026-05-01 收录
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Pancreatic development requires appropriate environmental cues, in which ECM-Integrin signaling plays a central role in the process. Specifically, we investigated how ECM-Integrin signaling in Ngn3+ cell (endocrine progenitors) regulates islet architecture and functions. Here we showed disruption of ECM-Integrin signaling affects beta cell functional maturation and potential non-autonomous regulation around islets. Four biological replicates were analyzed for wildtype and Itgb1 mutant

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2023-09-15
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