A curated dataset and web application for Integrative Analysis of Ancient DNA from Britain and Ireland

In recent years, genome-wide data from thousands of ancient human remains have been sequenced, offering unprecedented insights into past populations. This vast dataset of ancient human genomes and their associated metadata holds immense value for archaeologists, anthropologists, and biologists. However, extracting insights often requires advanced bioinformatics knowledge, creating barriers for non-experts. To address this challenge, we present a curated dataset and user-friendly web application for published genome-wide data from ancient Britain and Ireland, including new data produced by the COMMIOS Project. In this repository, we provide Gzip files for: Curated Metadata: A manually curated dataset with detailed information on geographic location, temporal classification, sample quality, raw sequencing data accession numbers, and other relevant attributes (COMMIOS_aadr_ref_v62.tsv.gz). Genotypes: Provided in EIGENSTRAT format, including genotype calls for approximately 1.23 million SNPs (1240k) and the Human Origins array with 597,573 sites (HO). Version History: May 2025 - v1.0.0 First version released based on AADR V62: The complete dataset includes 1,108 ancient British and Irish individuals, 1,164 modern individuals and 4,618 ancient Western European individuals.近年来，数千例古代人类遗骸的全基因组数据已完成测序，为解析古代人群提供了前所未有的研究视角。这一庞大的古代人类基因组数据集及其配套元数据（metadata），为考古学家、人类学家与生物学家带来了极高的研究价值。然而，从中挖掘研究见解往往需要掌握先进的生物信息学（bioinformatics）知识，这为非专业研究者设置了技术门槛。为应对这一挑战，我们发布了一套经人工整理的数据集与易用型网页应用程序，涵盖已发表的不列颠与爱尔兰地区古代人群全基因组数据，同时包含由COMMIOS项目（COMMIOS Project）产出的新增数据。 在本数据仓库中，我们提供以下Gzip压缩文件： - 整理后元数据：一套经人工梳理的数据集，包含地理区位、年代分类、样本质量、原始测序数据登录号及其他相关属性的详细信息，对应文件为COMMIOS_aadr_ref_v62.tsv.gz。 - 基因型数据：以EIGENSTRAT格式提供，包含约123万个1240k单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs）位点的基因型分型结果，以及搭载597573个位点的人类起源芯片（Human Origins array, HO）数据。 版本更新历史： 2025年5月 - v1.0.0 基于AADR V62发布的首个版本： 完整数据集涵盖1108例不列颠与爱尔兰地区古代个体、1164例现代个体，以及4618例西欧古代个体。