Baseline characteristics and unadjusted associations with incident CHD events (n = 2193; number of CHD events = 351).

Abbreviations: SD: standard deviation; HR: hazard ratio; CI: confidence interval; HDL: high-density lipoprotein; LDL: low-density lipoprotein; GFR: glomerular filtration rate.*p for trend.†Physical activity was assessed by questionnaire about all types of walking and exercise performed in the prior week [14].‡Defined by self-report of hypertension and use of anti-hypertensive medications, or measured SBP≥140 and/or DBP≥90 mmHg.∥Expressed as median (25%–75%), because of skewed distribution. The effect of the logarithm of the covariates on the CHD is measured.¶Classes of CHD risk at 10 years, according to Framingham functions [2].#Glomerular filtration rate (GFR) was estimated using the MDRD equation: GFR = 175 * Creatinine−1.154 * Age−0.203 * (1.212*Iblack+Iwhite)* (0.742*Ifemale+Imen) [32].**Quartiles were used instead of clinical cut-offs to avoid categories with few participants. In particular, categories of GFR