Escherichia coli Gene ydeA Encodes a Major Facilitator Pump Which Exports l-Arabinose and Isopropyl-β-d-Thiogalactopyranoside

Inactivation of the Escherichia coli gene ydeA, which encodes a member of the major facilitator superfamily, decreased the efflux of l-arabinose, thereby affecting the expression of AraC-regulated genes. In addition, overexpression of ydeA decreased the expression of genes regulated by isopropyl-β-d-thiogalactopyranoside.