The investigation of genes among normal tenocytes and inflammtory tenocytes

Tendinopathy is a common disease of the musculoskeletal system, however, the mechanism of tendinopathy has not yet been elucidated, and there are no clear conclusions about the changes in gene expression within tendinopathy. In order to better investigate the mechanisms inherent to the development of tendinopathy, we performed RNA sequencing on normal tendon cells and inflammatory tendon cells Overall design: In the present study, tendon cells were used for the assay, no stimulation was added to the control tendon cells(50ng/ml), and IL-1ß was added to the experimental cells, and the stimulation duration was 24 hours.