Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors

Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, SODIUM ION, ... Authors: Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, H, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S. Deposit date: 2016-10-14 Release date: 2017-04-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors. Bioorg. Med. Chem. Lett., 27, 2017

新型氨基苯并异恶唑衍生物作为可口服凝血因子IXa（factor IXa）抑制剂的发现
描述项：2-[N-环己基氨基]乙烷磺酸（2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID）、凝血因子IX（Coagulation factor IX）、钠离子（SODIUM ION）等。
作者：Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, H, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S.
存档日期：2016-10-14
发布日期：2017-04-26
最后更新日期：2024-11-06
实验方法：X射线衍射（X-RAY DIFFRACTION，1.54 Å）
引用文献：新型氨基苯并异恶唑衍生物作为可口服凝血因子IXa抑制剂的发现。Bioorg. Med. Chem. Lett., 27, 2017