CollecTRI Data for Investigation of SETBP1 gene expression and transcription factor activity across human tissues

Here we provide the human CollecTRI prior (accessed May 2023) for inference of TF activity across 31 GTEx tissues using multivariate linear modeling method decoupleR.<br> <br> The `human_prior_tri.csv` includes 1,178 unique TFs (referred to as the source) that target 6,627 unique genes (referred to as targets) to give us 42,595 interactions in the CollecTRI prior input. Interactions are represented as a + or - 1 (mor).本研究提供2023年5月获取的人类CollecTRI先验数据集，用于借助多元线性建模方法decoupleR，对31个GTEx组织中的转录因子（Transcription Factor，TF）活性进行推断。 `human_prior_tri.csv` 文件包含1178个独特的转录因子（被定义为调控源），这些转录因子靶向6627个独特的基因（被定义为调控靶标），在CollecTRI先验输入中共计得到42595条互作关系。每条互作关系以+1或-1（mor）进行标注。