target genomics

NIAID Data Ecosystem2026-03-12 收录

碱基编辑

氨基酸替换

数据链接：

https://www.omicsdi.org/dataset/node/OEX00012006 数据链接链接失效反馈

官方服务：

资源简介：

Examination of base substitutions induced by the transformer base editor (tBE)

创建时间：

2021-03-12

Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in Facioscapulohumeral muscular dystrophy

FSHD面肩肱型肌营养不良症

碱基编辑

Facioscapulohumeral muscular dystrophy (FSHD) is caused by chromatin relaxation of the D4Z4 repeat resulting in misexpression of the D4Z4-encoded DUX4 gene in skeletal muscle. One of the key genetic r

NIAID Data Ecosystem50

dual gRNA system achieve efficient C-to-T&G-to-A,A-to-G&T-to-C base editing

基因编辑

碱基编辑

dual gRNA system achieve efficient C-to-T&G-to-A,A-to-G&T-to-C base editing

NIAID Data Ecosystem30

Amino acid substitutions specific for subgroups Armenia 1 and Armenia 2 of the Europe 1 lineage.

病毒亚群分型

氨基酸替换

Amino acid substitutions specific for subgroups Armenia 1 and Armenia 2 of the Europe 1 lineage.

NIAID Data Ecosystem10

Programmable RNA base editing with a single engineered protein

碱基编辑

基因治疗

Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro

NIAID Data Ecosystem40

GO: A functional reporter system to identify and enrich base editing activity

碱基编辑

基因工程工具开发

This study developed tools for enriching base editing events in mouse and human cell lines

NIAID Data Ecosystem20