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Details of SIP PIR overlap with GWAS Variants.

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NIAID Data Ecosystem2026-03-13 收录
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Each sheet in the Excel file provides information for the SIP PIRs that overlap with a relevant GWAS variant, for each of the five cell types (Ery = erythrocytes; MacMon = macrophages/monocytes; MK = megakaryocytes; nCD4 = naive CD4 T-cells; Neu = neutrophils). The columns baitID, baitChr, baitStart, baitEnd, and baitName pertain to the promoter bait identifier, gene(s), and bait location (from the Javierre et al. [1] pcHi-C data). The columns oeStart, oeEnd, oeID, and oeName pertain to the other end (PIR) location, identifier, and gene(s). The column specific indicates if the SIP gene is only found in this particular cell type (i.e., a cell type-specific SIP). The remaining columns pertain to the GWAS variants: Phenotype, VariantID, rsID, Position (hg19 base pair location of variant), pval, ancestry, and data (Vuckovic et al. [2] or Chen et al. [3]). The column “ATACseq_olap” denote whether the variant overlaps with cell-type-specific ATAC-seq peaks and the column “Motifs_genename” annotates transcription factor binding motifs the variant disrupts. (XLSX)

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2022-01-31
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