Logistic regression model of primary risk factors for preeclampsia including presence of the ACCG <i>COMT</i> haplotype.

COMT haplotype SNP order: rs6269, rs4633, rs4818, rs4680. S.E., standard error; C.I., confidence interval; BMI, body mass index. When both maternal and fetal ACCG haplotypes from the maternal-fetal dyads were included in a single model, the maternal ACCG COMT remained significantly associated with reduced risk for preeclampsia. The fetal ACCG COMT haplotype is not associated with risk for preeclampsia after correcting for shared genetics between the mother and fetus.