BENEFICIAL PROPERTIES OF NIGELLA SATIVA (BLACK CUMIN)

systems across the Middle East, North Africa, and South Asia. Modern biomedical research increasingly validates its pharmacological potential, attributing diverse therapeutic effects primarily to its bioactive compound thymoquinone. Findings suggest that Nigella sativa demonstrates significant therapeutic promise, although further standardized clinical trials are required to confirm dosage safety and long-term efficacy. Evidence from both in vitro, in vivo, and clinical research suggests that Nigella sativa demonstrates significant therapeutic potential across multiple physiological systems. However, despite promising results, challenges remain regarding dosage standardization, extraction methods, and the need for large-scale randomized clinical trials. The findings highlight the potential of Nigella sativa as a valuable natural therapeutic agent and emphasize the need for further research to establish standardized clinical applications.黑种草（Nigella sativa）广泛分布于中东、北非及南亚区域。现代生物医学研究正持续验证其药理活性，其多样的治疗功效主要源于其活性成分百里醌（thymoquinone）。现有研究表明，黑种草具备显著的治疗应用前景，但仍需开展标准化临床试验以明确其给药安全性与长期疗效。 体外（in vitro）、体内（in vivo）及临床研究的证据均显示，黑种草在多生理系统中展现出可观的治疗潜力。尽管已取得诸多积极结果，但仍存在给药标准化、提取工艺优化以及开展大规模随机对照临床试验等方面的挑战。 本研究结果凸显了黑种草作为极具价值的天然治疗制剂的潜力，并强调需开展进一步研究以确立其标准化临床应用方案。