FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine

FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine Descriptor: 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH Authors: Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R. Deposit date: 2012-05-23 Release date: 2012-06-27 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh. Biochemistry, 51, 2012

FimH凝集素结构域（FimH lectin domain）与O-连接丙炔基吡啶的α-D-甘露糖苷（alpha-D-mannoside）形成共晶复合物。配体描述符：3-(吡啶-3-基)丙-2-炔-1-基 α-D-吡喃甘露糖苷（3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside），FimH。作者：布卡埃（Bouckaert, J）、图亚伊比亚（Touaibia, M）、鲁斯（Roos, G）、萧（Shiao, T.C）、王（Wang, Q）、帕帕多普洛斯（Papadopoulos, A）、罗伊（Roy, R.）。提交日期：2012-05-23，发布日期：2012-06-27，最后修改日期：2024-11-13。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.9埃（Å）。引用：《细菌黏附素FimH受体结合位点中作为潜在熵杠杆的酪氨酸门控》，《生物化学（Biochemistry）》，第51卷，2012年。