Replication Data for: Discovering non-additive heritability using additive GWAS summary statistics

This repo contains data produced from the manuscript entitled: "Discovering non-additive heritability using additive GWAS summary statistics". Here, we provide the additive and cis-interaction LD scores used for the real data analyses of 25 well-studied quantitative phenotypes from 349,468 individuals of self-identified European ancestry in the UK Biobank and up to 159,095 individuals in BioBank Japan. Note that for the UK Biobank analysis, LD scores were computed using a reference panel of 489 individuals from the European superpopulation (EUR) of the 1000 Genomes Project. For the analysis of BioBank Japan, In order to analyze data from BioBank Japan, we downloaded publicly available GWAS summary statistics for the 25 traits from http://jenger.riken.jp/en/result. Summary statistics used age, sex, and the first ten principal components as confounders in the initial GWAS study. We then used individuals from the East Asian (EAS) superpopulation from the 1000 Genomes Project Phase 3 to calculate paired LD scores from a reference panel.