Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6.

Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6. Descriptor: (2~{S})-1-[(2~{S})-2-[[(1~{S})-1-[(2~{S})-1-[(2~{S})-2-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]-2-oxidanyl-2-oxidanylidene-ethyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Cozier, G.E, Acharya, K.R. Deposit date: 2019-12-23 Release date: 2020-04-01 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020

与SG6结合的Res_S2突变体人血管紧张素-1转换酶（Angiotensin-1 converting enzyme）N结构域晶体结构。描述内容：(2S)-1-[(2S)-2-[[(1S)-1-[(2S)-1-[(2S)-2-氨基-4-羟基-4-氧代丁酰基]吡咯烷-2-基]-2-羟基-2-氧代乙基]氨基]丙酰基]吡咯烷-2-羧酸、1,2-乙二醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖等。作者：Cozier, G.E.、Acharya, K.R.。存放日期：2019-12-23；发布日期：2020-04-01；最后修改日期：2024-11-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.7埃。引用文献：ACE结构域的选择性可超出活性位点直接相互作用残基范围，《Biochem.J.》，第477卷，2020年。