Kinetic parameters obtained from endocytosis assays performed with cells heterologously co-expressing MOP-YFP and c-myc-5-HT2C-Cerulean receptors.
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Cells were treated with DAMGO (10 μM), sufentanyl (1 μM), methadone (10 μM), morphine (10 μM), morphine (10 μM) plus 5-HT (10 μM), morphine (10 μM) plus DOI (10 μM), morphine (10 μM) plus WAY161503 (1 μM), oxycodone (10 μM) plus 5-HT (10 μM) or buprenorphine (10 μM) plus 5-HT (10 μM). Data indicate mean ± SEM of (n) independent experiments. t1/2: time to reach the 50% of the maximal response (minutes). Emax: maximal response (number of vesicles per cell). n.d.: not detected.Kinetic parameters obtained from endocytosis assays performed with cells heterologously co-expressing MOP-YFP and c-myc-5-HT2C-Cerulean receptors.
创建时间：
2015-12-03
