Cytomegalovirus vaccine vector-induced effector memory CD4+ T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza

To investigate the transcriptional response in whole blood from administration of the Cytomegolovirus vaccine vector against heterologous avian flu Comparative gene expression analysis cynomolgus macaque whole blood RNA-seq data of each time point in vaccination regimen of 68-1 CyCMV/flu or full length CyCMV/flu. Regimen consisted of prime given at D0 and boost at D105. All animals were challenged after vaccination with avian influenza H5N1 virus