Synthesis of 2,3-Diarylisoindolin-1-one by Copper-Catalyzed Cascade Annulation of 2‑Formylbenzonitriles, Arenes, and Diaryliodonium Salts
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A three-component cascade cyclization was developed to synthesize 2,3-diarylisoindolin-1-one by using 2-formylbenzonitrile, arenes, and diaryliodonium salts. The process underwent copper-catalyzed tandem C–N/C–C bond formation, producing isoindolin-1-one derivatives in good to excellent yields.
创建时间：
2017-10-09
