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A first exon termination checkpoint that preferentially suppresses extragenic transcription [RNASEQ_BMDM_polyA]

NIAID Data Ecosystem2026-04-29 收录

转录终止调控

基因间区转录抑制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP202029 数据链接链接失效反馈

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资源简介：

Wdr82 and Zc3h4 repress transcription at extragenic sites. Overall design: Transcriptome analysis to measure transcription in cells depleted of Wdr82, Zc3h4or other known termination factors.

应用场景：

创建时间：

2021-05-04

转录终止调控

RNA聚合酶功能研究

RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been shown to regulate serine 5 phosphorylation

NIAID Data Ecosystem70

PP1 PNUTS binds the “restrictor” and dephosphorylates pol II CTD Ser5 to stimulate RNA pol II transcription termination [eNET-seq]

转录终止调控

RNA聚合酶转录

The restrictor complex, WDR82/ZC3H4, is the major termination factor for antisense transcription from bidirectional promoters, but its mechanism of action is poorly understood. We report that the PP1

NIAID Data Ecosystem30

Herpes Simplex Virus blocks host transcription termination via the bimodal activities of ICP27.

病毒-宿主相互作用

转录终止调控

Infection by viruses, including Herpes Simplex virus-1 (HSV-1), and cellular stresses cause widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII). The underlying mech

NIAID Data Ecosystem30

Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation

转录终止调控

piRNA引导异染色质形成

Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation

integrated proteome resources60

RNAseq of Bacillus subtilis wildtype and cspB-cspD deletion mutant reveals that the lack of the cold shock proteins CspB and CspD affects the expression of about 20% of all genes. RNAseq of Bacillus subtilis wildtype and cspB-cspD deletion mutant reveals that the lack of the cold shock proteins CspB and CspD affects the expression of about 20% of all genes

冷休克蛋白

转录终止调控

RNAseq of coding RNA in Bacillus subtilis wildtype and deletion strain GP1971 genotype trpC2 ΔcspB::cat ΔcspD::aphA3 using rRNA depleted mRNA and Illumina TruSeq stranded mRNA libraries, sequenced on

NIAID Data Ecosystem30

A first exon termination checkpoint that preferentially suppresses extragenic transcription [RNASEQ_BMDM_polyA]

资源简介：

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