Single cell genomic analyses are critical for reproductive biology since each germline cell has a unique genome due to homologous recombination. Genomes of single sperm cells have been sequenced recen
This is a collection of sequenced cardiac mitochondrial DNA from individuals with and without Down syndrome. The goal of the study was to compare genomic variation in the heart tissue from those with
Pathogenic germline mitochondrial genome (mtDNA) mutations cause debilitating and often fatal diseases in children. Mitochondrial replacement therapies (MRT) circumventing mother to child transmission
