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Role of DYRK1A in MPN

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP428937
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We aim to investigate the role of DYRK1A gene in MPN pathogenesis by DYRK inhibitor and genetic knockout Overall design: RNA-sequencing was performed in SET2 DYRK1A KO clone 11H1 and 14B5 generated by CRISPR/Cas9. Wild-type SET2 cells was included as a control. DYRK1A KO clones 11H1 and 14B5 were compared to wild-type SET2 cells repsectively (3x3 analysis).
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2025-06-27
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