Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor 1 receptor (Csf1r) gene
We used microarray to examine changes in gene expression in the absence of Csf1r in the brain and spleen. Spleen gene expression was compared to BMDM to identify splenic-specific genes. RNA was isolat