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Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1 (ChIP-Seq)

ChEBI2012-06-19 更新2026-07-21 收录

亨廷顿病分子机制

ChIP-seq分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38000 数据链接链接失效反馈

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Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1 (ChIP-Seq)

应用场景：

创建时间：

2012-06-19

ChIP-seq分析

果蝇遗传学

Drosophila Atro mutants have a large range of phenotypes, including neurodegeneration, segmentation, patterning and planar polarity defects. Although Atro mutants have diverse phenotypes, little is kn

NIAID Data Ecosystem40

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq). Mus musculus

亨廷顿病分子机制

表观遗传调控

Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain.

NIAID Data Ecosystem30

WhiB4 is required for the reactivation of latent infection of Mycobacterium marinum in zebrafish [ChIP-Seq]

结核病感染

ChIP-seq分析

Granulomas are the pathological hallmark of tuberculosis (TB). In individuals latently infected with Mycobacterium tuberculosis (M. tb), the bacteria are thought to reside within the granulomas in a n

NIAID Data Ecosystem20

Otx2 ChIP-seq in the adult mouse Retinal Pigmented Epithelium (RPE) and neural retina. Mus musculus

ChIP-seq分析

视网膜基因调控

Otx2 has been shown to be non cell autonomously required for photoreceptor cell survival in the adult mouse RPE. This study aims to identify Otx2 DNA binding profile in both RPE and neural retina to i

NIAID Data Ecosystem40

H3K9acS10P (new abcam lot).Kc

组蛋白修饰定位

ChIP-seq分析

modENCODE_submission_3009 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the l

NIAID Data Ecosystem30

Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1 (ChIP-Seq)

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