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Investigation of 3D Chromatin Architecture Rewiring During Muscle Satellite Cells activation and aging

NIAID Data Ecosystem2026-05-01 收录

3D染色质构象

干细胞衰老

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE189842 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-06-01

干细胞衰老

单细胞转录组学

Ageing of the hematopoietic stem cell (HSC) compartment is characterized by skewing towards the myeloid lineage and reduced stem cell function, the molecular basis of which is largely unknown. Using s

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Aged Hematopoietic Stem Cells Drive Aging-Associated Immune Remodeling

干细胞衰老

免疫系统重建

Phenotypic and functional changes seen in the aged adaptive immune system are primarily driven by aging of hematopoietic stem cells (HSCs), pharmacological rejuvenated aged HSCs were able to reconstit

NIAID Data Ecosystem30

Urbanus and Cosgrove et al. Nature Communications (2023). DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

干细胞衰老

髓系细胞生成

Ageing is associated with changes in the cellular composition of the immune system. During ageing, hematopoietic stem and progenitor cells (HSPCs) that produce immune cells are thought to decline in t

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Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells [ChIP-seq]

干细胞衰老

ATF4转录因子ChIP-seq

Human acute myeloid leukemia (AML) KG1a cells or mouse BM cells (mouse bone morrow cells were employed for each ChIP assay. The ChIP procedure was performed according to a previously described protoc

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Transcription profiling of human mesenchymal stem cells to determine changes over the course of cellular aging

干细胞衰老

转录组学分析

Transcription profiling of human mesenchymal stem cells to determine changes over the course of cellular aging

ChEBI2008-10-20 更新30