Crystal structure of Aspergillus fumigatus chitinase B1 in complex with allosamidin

NIAID Data Ecosystem2026-05-01 收录

几丁质酶-变构霉素复合物结构

抗菌药物设计

数据链接：

https://www.rcsb.org/structure/2A3E 数据链接链接失效反馈

官方服务：

资源简介：

Crystal structure of Aspergillus fumigatus chitinase B1 in complex with allosamidin

创建时间：

2023-10-25

SCYTALONE DEHYDRATASE AND CYANOCINNOLINE INHIBITOR

结构生物学

抗菌药物设计

SCYTALONE DEHYDRATASE AND CYANOCINNOLINE INHIBITOR Descriptor: 4-(3,3-diphenylpropylamino)cinnoline-3-carbonitrile, CALCIUM ION, PROTEIN (SCYTALONE DEHYDRATASE) Authors: Chen, J.M, Xu, S.L, Wawrzak, Z

Protein Data Bank Japan2023-09-13 更新70

QSAR_Based_肉桂醛氨基酸席夫碱化合物抗真菌活性设计数据

抗菌药物设计

QSAR定量构效关系

本数据集围绕肉桂醛氨基酸席夫碱（CAAS）化合物的定量构效关系（QSAR）设计展开，包含针对黑曲霉和产黄青霉的QSAR模型构建、验证结果，以及基于模型设计合成的2种高活性新化合物的抗真菌测试数据，为新型抗真菌剂研发提供支撑。

海数据50

Exploring Long Arm Amide-Linked Side Chains in the Design of Antifungal Azole Inhibitors of Sterol 14α-Demethylase (CYP51)

抗菌药物设计

CYP51抑制剂

The rise in fungal drug resistance has exacerbated the treatment of invasive fungal infections, most commonly caused by Candida. This research describes the synthesis of extended “long-arm” azole anti

NIAID Data Ecosystem10

Amino Acid Substitutions at the Major Insertion Loop of Candida albicans Sterol 14alpha-Demethylase Are Involved in Fluconazole Resistance

真菌耐药性

抗菌药物设计

BackgroundIn the fungal pathogen Candida albicans, amino acid substitutions of 14alpha-demethylase (CaErg11p, CaCYP51) are associated with azole antifungals resistance. This is an area of research whi

Figshare2016-01-18 更新60

Sequence diversity of apidaecin-like peptides arresting the terminating ribosome

抗菌肽核糖体抑制

抗菌药物设计

The Proline-rich Antimicrobial Peptide (PrAMP) apidaecin (Api) inhibits translation by binding in the ribosomal nascent peptide exit tunnel, trapping release factors RF1 or RF2, and arresting ribosome

NIAID Data Ecosystem10

Crystal structure of Aspergillus fumigatus chitinase B1 in complex with allosamidin

资源简介：

相关数据集