We report the global gene expression effects in TSC-deficient and TSC wild type cells after treatemnet with. CDK7 inhibitor(THZ1), we performed RNA-Seq on TSC1-null HCV.29 cells and TSC1-intact HCV.29
For the parameters k, c, Δe, and γ, their values were increased and decreased by 50% (shown in parentheses) in the sensitivity analysis. The parameters N, T, and tp were kept fixed for our simulations
*values derived from Comin et al.[10]. §values based on van der Goot et al.[13]. Footnote: values of parameters a, b, sL, rL, sI, rI, s and r are those previously reported in Table 1.